Primary Identifier | IPR033361 | Type | Family |
Short Name | RETREG3 |
description | Reticulophagy regulator 3 (RETREG3), also known as FAM134C, mediates NRF1-enhanced neurite outgrowth. NRF1 (nuclear respiratory factor-1) is a major transcription factor that can positively regulate FAM134C []. Members of the FAM134 protein family, including FAM134C, are ER-resident receptors that bind to autophagy modifiers LC3 and GABARAP, and facilitate ER degradation by autophagy []. |