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Allele : Hcn2<ap> hyperpolarization-activated, cyclic nucleotide-gated K+ 2; apathetic

Primary Identifier  MGI:3838227 Allele Type  Spontaneous
Attribute String  Hypomorph Gene  Hcn2
Inheritance Mode  Recessive Strain of Origin  DW/Pas
Is Recombinase  false Is Wild Type  false
molecularNote  Four base pairs (TTCA) were duplicated at nucleotide position 1669 in the cyclic nucleotide binding domain. RT-PCR confirmed a 90% decrease in transcript expression. The absence of protein expression was confirmed by immunohistochemistry on brain sections.
  • mutations:
  • Duplication
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele