| First Author | Rugarli EI | Year | 1995 |
| Journal | Nat Genet | Volume | 10 |
| Issue | 4 | Pages | 466-71 |
| PubMed ID | 7670496 | Mgi Jnum | J:26310 |
| Mgi Id | MGI:74933 | Doi | 10.1038/ng0895-466 |
| Citation | Rugarli EI, et al. (1995) Different chromosomal localization of the Clcn4 gene in Mus spretus and C57BL/6J mice [see comments]. Nat Genet 10(4):466-71 |
| abstractText | We report the unprecedented finding of a gene with a different map position in two mouse strains. The Clcn4 gene was found to map to the X chromosome in the wild Mediterrean mouse, Mus spretus but to chromosome 7 in the inbred strain of laboratory mouse C57BL/6J. These data indicate that a recent evolutionary rearrangement occurred on the mouse sex chromosomes, very close to the pseudoautosomal region. Our data provide molecular evidence for a major divergence near the pseudoautosomal region, consistent with the hypothesis that hybrid sterility in these species results from abnormal pairing of sex chromosomes during male meiosis. |
