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Protein Coding Gene : Rab1a RAB1A, member RAS oncogene family
Primary Identifier  MGI:97842 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  19324
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTP binding activity and GTPase activity. Involved in cell migration; melanosome transport; and substrate adhesion-dependent cell spreading. Located in Golgi apparatus and melanosome. Is expressed in several structures, including diaphragm and genitourinary system. Orthologous to human RAB1A (RAB1A, member RAS oncogene family).
PHENOTYPE: Mice homozygous for a null allele exhibit complete embryonic lethality during organogenesis. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13745,
  • Rab1,
  • Gtbp,
  • name unknown at this time 12/9/92,
  • members RAS oncogene family,
  • ras-related YPT1 protein,
  • Rab1a,
  • MGD-MRK-13744,
  • MGD-MRK-15847,
  • RAB1, member RAS oncogene family,
  • Ypt1,
  • MGD-MRK-10329,
  • RAB1A, member RAS oncogene family,
  • Rab-1,
  • mKIAA3012,
  • ypt-1 ras-related GTP binding protein
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Features --> Cross References

Genome

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1 Involved In Mutations

Trail: ProteinCodingGene

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3 Transgenic Expressors

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

20 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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