Primary Identifier | MGI:1916604 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 69354 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables L-arginine transmembrane transporter activity and neutral L-amino acid:sodium symporter activity. Involved in L-alanine import across plasma membrane and L-arginine transmembrane transport. Predicted to be located in microvillus membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; gut; liver; and lung. Orthologous to human SLC38A4 (solute carrier family 38 member 4). PHENOTYPE: Mice heterozygous for a paternally inherited null allele or homozygous for the allele exhibit postnatal lethality, decreased placenta weight, decreased fetal size, thin labyrinth, impaired trophoblast proliferation and glycogen cells, and reduced amino acid circulation. [provided by MGI curators] |