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Allele : Tg(Bmi1-cre/ERT2)1Fjs transgene insertion 1, Frederick J de Sauvage

Primary Identifier  MGI:5294806 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Bmi1-cre/ERT2)1Fjs
Strain of Origin  C57BL/6 Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  A BAC (RP23-181D14) containing the Bmi1 locus was modified via recombineering methods by insertion of an IRES-cre/ERT2-pA-Frt-neo-Frt cassette at 85 base pairs 3' of the stop codon of Bmi1. The neo cassette was deleted by transforming the modified BAC into arabinose-induced cells expressing Flp. The final vector was injected into C57BL/6 blastocysts to generate germline-transmitting mice.
  • mutations:
  • Insertion
  • synonyms:
  • Bmi1CreER,
  • Bmi1CreER
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

2 Publication categories

Trail: Allele