| First Author | Lee HJ | Year | 2000 |
| Journal | Biochim Biophys Acta | Volume | 1493 |
| Issue | 1-2 | Pages | 273-8 |
| PubMed ID | 10978538 | Mgi Jnum | J:64515 |
| Mgi Id | MGI:1889437 | Doi | 10.1016/s0167-4781(00)00183-4 |
| Citation | Lee H, et al. (2000) Molecular cloning and expression of aminopeptidase A isoforms from rat hippocampus(1). Biochim Biophys Acta 1493(1-2):273-8 |
| abstractText | The full-length cDNA encoding aminopeptidase A (APAL) was cloned from a rat hippocampus cDNA library. A short variant aminopeptidase A (APAS), produced by deletion, was also cloned. In the case of APAL, the longest open reading frame encodes 945 amino acid residues with a calculated molecular mass of 108 kDa, and the deduced amino acid sequence shows 76, 86 and 78% identity with its human, murine and porcine counterparts, respectively. Rat aminopeptidase A mRNAs were detected in the kidney, liver, heart and brain by Northern blot analysis. When overexpressed in COS-1 cells, APAL shows apparent aminopeptidase A activity, whereas APAS does not. |
