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Protein Coding Gene : Kif5b kinesin family member 5B

Primary Identifier  MGI:1098268 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  16573
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable several functions, including ATP hydrolysis activity; JUN kinase binding activity; and microtubule lateral binding activity. Involved in positive regulation of GABAergic synaptic transmission; regulation of modification of synapse structure, modulating synaptic transmission; and stress granule disassembly. Acts upstream of or within several processes, including cellular response to type II interferon; mitocytosis; and organelle transport along microtubule. Located in several cellular components, including ciliary rootlet; mitochondrion; and phagocytic vesicle. Is active in postsynaptic cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human KIF5B (kinesin family member 5B).
PHENOTYPE: Mice homozygous for disruptions in this gene die as embryos during organogenesis, exhibit growth retardation and fail to turn during gastrulation. [provided by MGI curators]
  • synonyms:
  • MGI:2147285,
  • kinesin family member 5B,
  • AL022807,
  • expressed sequence AL022807,
  • Khc,
  • Kif5b,
  • kinesin heavy chain

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

16 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For