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Comment :

Type  MGI:General Description  tamoxifen treated mice show numerous white areas on the retina which form fluffy white patches or are dot-like at 8 weeks of age and look like hard exudates and cotton wool spots seen in humans with diabetic retinopathy tamoxifen treated mice show capillaries that penetrate the inner limiting membrane of the retina and grow into the vitreous body to cause proliferative retinopathy at about 6 weeks of age