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Protein Coding Gene : Neil2 nei like 2 (E. coli)

Primary Identifier  MGI:2686058 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  382913
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables microtubule binding activity. Predicted to be involved in base-excision repair. Predicted to act upstream of or within DNA repair. Located in cytoplasm and mitotic spindle. Is expressed in primordial germ cell of gonad. Orthologous to human NEIL2 (nei like DNA glycosylase 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased age-related DNA damage, loss of telomeres and increased induced lung inflammation. [provided by MGI curators]
  • synonyms:
  • NEH2,
  • LOC382913,
  • nei like 2 (E. coli),
  • Neil2,
  • gene model 1212, (NCBI),
  • Gm1212

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For