| Primary Identifier | MGI:1920175 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 72925 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables ubiquitin protein ligase activity. Involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Located in bounding membrane of organelle; endoplasmic reticulum membrane; and trans-Golgi network membrane. Is expressed in central nervous system. Orthologous to human MARCHF1 (membrane associated ring-CH-type finger 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal dendritic cell morphology and physiology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
