Primary Identifier | MGI:6269989 | Allele Type | Transgenic |
Attribute String | Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence | Gene | Tg(CAG-GCH1)#Wlf |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains the following elements: the CAG promoter, a loxP site, a neomycin resistance gene (including stop codon and poly(A) signal) a second loxP site, the human GCH1 cDNA with HA tag sequence coupled to it, and poly(A) signal sequence. This creates a conditional-ready allele that will express HA-tagged human GCH1 only after cre-mediated removal of the neo cassette. |