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Allele : Rad50<tm1Flv> RAD50 double strand break repair protein; targeted mutation 1, Richard A Flavell
Primary Identifier  MGI:3527268 Allele Type  Targeted
Gene  Rad50 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
description  RHS7 makes up one component of a locus control region for TH2 cytokines.
molecularNote  The RHS7 site (Rad50 hypersensitive site 7), a 637 bp region located in intron 24, was replaced with a floxed neomycin resistance cassette. The resistance cassette was subsequently removed from the ES cells by transient cre expression. There was no effect on Rad50 expression.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • RHS7-deficient,
  • RHS7-deficient
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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