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Allele : Ikbkb<tm2Mka> inhibitor of kappaB kinase beta; targeted mutation 2, Michael Karin

Primary Identifier  MGI:2445462 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ikbkb
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = GS (Genome Systems).
molecularNote  LoxP sites were inserted that flank exon 3, which encodes the ATP binding site of the catalytic domain. An adjacent neomycin selection cassette was removed in ES cells by transient Cre expression prior to the production of chimeric mice.
  • mutations:
  • Insertion
  • synonyms:
  • IkkBeta<F>,
  • Ikkbeta<loxP>,
  • IKKbeta flox,
  • Ikbk2<fx>,
  • Ikbk2<fx>,
  • IkkBeta<F>,
  • IKKBeta<fl>,
  • Ikkbeta<loxP>,
  • IKKbeta flox,
  • IKKBeta<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

136 Publication categories

Trail: Allele