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Protein Coding Gene : Pold2 polymerase (DNA directed), delta 2, regulatory subunit

Primary Identifier  MGI:1097163 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  18972
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA binding activity. Involved in DNA biosynthetic process. Part of delta DNA polymerase complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and hemolymphoid system. Orthologous to human POLD2 (DNA polymerase delta 2, accessory subunit).
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation and failure of blastocysts to hatch from the zona pellucida with increased cell death during outgrowth culture. [provided by MGI curators]
  • synonyms:
  • p50,
  • Pold2,
  • po1D2,
  • 50kDa,
  • polymerase (DNA directed), delta 2, regulatory subunit

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

41 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For