First Author | Reilly KM | Year | 2008 |
Journal | Cell | Volume | 135 |
Issue | 3 | Pages | 408-10 |
PubMed ID | 18984150 | Mgi Jnum | J:143214 |
Mgi Id | MGI:3823175 | Doi | 10.1016/j.cell.2008.10.009 |
Citation | Reilly KM, et al. (2008) It takes a (dysfunctional) village to raise a tumor. Cell 135(3):408-10 |
abstractText | The tumor microenvironment is known to play an important role in tumorigenesis. In this issue, Yang et al. (2008) demonstrate that mast cells heterozygous for the Nf1 gene promote the growth of neurofibromas in a mouse model of neurofibromatosis and that genetic and pharmacological inhibition of these cells is sufficient to block tumor growth. |