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Publication : It takes a (dysfunctional) village to raise a tumor.

First Author  Reilly KM Year  2008
Journal  Cell Volume  135
Issue  3 Pages  408-10
PubMed ID  18984150 Mgi Jnum  J:143214
Mgi Id  MGI:3823175 Doi  10.1016/j.cell.2008.10.009
Citation  Reilly KM, et al. (2008) It takes a (dysfunctional) village to raise a tumor. Cell 135(3):408-10
abstractText  The tumor microenvironment is known to play an important role in tumorigenesis. In this issue, Yang et al. (2008) demonstrate that mast cells heterozygous for the Nf1 gene promote the growth of neurofibromas in a mouse model of neurofibromatosis and that genetic and pharmacological inhibition of these cells is sufficient to block tumor growth.
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