Primary Identifier | MGI:6452225 | Allele Type | Transgenic |
Attribute String | Transactivator | Gene | Tg(Rn1-rtTA2S*M2)#Cpmh |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The entire gene sequence (exons and introns) in BAC RP23-240p23 was replaced with a modified rtTA2 sequence (lower bakground activity, higher doxycycline sensitivity and changes to adapt it to eukaryotic cells). This brings the expression of the tetracycline reverse trans-activator under the control of the mouse renin promoter. |