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Allele : Ythdc2<em2Rspi> YTH domain containing 2; endonuclease-mediated mutation 2, Ramesh S Pillai
Primary Identifier  MGI:7466367 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Ythdc2
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Tryptophan codon 1375 (TGG) in exon 28 was changed to alanine (GCA )(p.W1375A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation inactivates the m6A-binding capacity of the YTH domain.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Ythdc2<YTH>,
  • Ythdc2<YTH>
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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