| Primary Identifier | MGI:1924281 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 77031 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in acrosome assembly and regulation of intracellular pH. Located in acrosomal vesicle and apical plasma membrane. Is expressed in several structures, including alimentary system; heart; metanephros; nervous system; and respiratory system. Orthologous to human SLC9A8 (solute carrier family 9 member A8). PHENOTYPE: Homozygotes for a null allele show male sterility, impaired mucin synthesis and bicarbonate secretion in the colon and elongation of the small intestine, cecum and ileum crypts. Homozygotes for another null allele show male sterility, asthenospermia, globozoospermia, and abnormal acrosome assembly. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
