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Protein Coding Gene : Fgf6 fibroblast growth factor 6

Primary Identifier  MGI:95520 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  14177
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within cartilage condensation and myoblast differentiation. Predicted to be located in sarcolemma. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; limb; and musculature. Orthologous to human FGF6 (fibroblast growth factor 6).
PHENOTYPE: Homozygotes for targeted null mutations appear phenotypically normal, but exhibit a defect in skeletal muscle regeneration following injury. Mutant myoblasts show decreased migrational ability. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-9765,
  • Fgf6,
  • Fgf-6,
  • MGD-MRK-9771,
  • fibroblast growth factor 6

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

43 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For