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Protein Coding Gene : Mcm6 minichromosome maintenance complex component 6

Primary Identifier  MGI:1298227 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  17219
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Contributes to DNA helicase activity and single-stranded DNA binding activity. Acts upstream of or within DNA unwinding involved in DNA replication. Located in nucleus. Part of MCM complex. Is expressed in several structures, including brain; eye; future brain; genitourinary system; and limb. Orthologous to human MCM6 (minichromosome maintenance complex component 6).
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit prenatal lethality. Mice heterozygous for this allele exhibit increased micronulei-containing red blood cells. [provided by MGI curators]
  • synonyms:
  • Mcmd6,
  • DNA segment, Chr 1, Wayne State University 22, expressed,
  • mini chromosome maintenance deficient 6 (S. cerevisiae),
  • D1Wsu22e,
  • MGI:106573,
  • MGD-MRK-34267,
  • Mcm6,
  • minichromosome maintenance complex component 6

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

15 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For