First Author | Hruban V | Year | 1978 |
Journal | J Immunogenet | Volume | 5 |
Issue | 3 | Pages | 173-8 |
PubMed ID | 567662 | Mgi Jnum | J:6033 |
Mgi Id | MGI:54510 | Doi | 10.1111/j.1744-313x.1978.tb00643.x |
Citation | Hruban V, et al. (1978) SLB, a new alloantigenic system of the pig. J Immunogenet 5(3):173-8 |
abstractText | An alloantigen segregating in the double back-cross families, distinct from serologically determinalble transplantation antigens controlled by the major histocompatibility complex (SLA), was detected in pigs by the complement-dependent lymphocytotoxic technique. The system was designated SLB and its product (antigen SLB-A1) was demonstrated in all lymphocytes from the lymph nodes, thymus and peripheral blood, but not in the erythrocytes. Back-cross matings supplied evidence of the dominant heredity of SLB-A1. Detection of further SLB antigens was unsuccessful, so that only two alleles (SLB-A1 and SLB-A-) could be determined in families. Double back-cross families revealed a close linkage between the SLB locus and the L blood group locus. Maximun lod score values were calculated in recombination fraction theta=theta.10. |