| Primary Identifier | MGI:2146012 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 105844 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable CARD domain binding activity. Predicted to be involved in negative regulation of cell migration involved in sprouting angiogenesis and positive regulation of protein localization to nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; gut; and tooth. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human CARD10 (caspase recruitment domain family member 10). PHENOTYPE: Mice homozygous for a null allele exhibit partial penetrance of anencephaly and subsequent perinatal lethality of anencephalic embryos. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
