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Allele : Dkc1<tm1.1Pjma> dyskeratosis congenita 1, dyskerin; targeted mutation 1.1, Philip J Mason
Primary Identifier  MGI:3809481 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dkc1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination of Dkc1tm1Pjma removed exon 15 and a neo cassette leaving a premature stop codon that had been introduced into exon 14. Northern and western blot analysis in ES cells confirmed the expression of a truncated transcript and protein at levels lower than that of wild-type transcript and protein.
  • mutations:
  • Intragenic deletion,
  • Single point mutation
  • synonyms:
  • Dkc1<delta15>,
  • Dkc1<delta15>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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