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Publication : Complement factor H and related proteins: an expanding family of complement-regulatory proteins?

First Author  Zipfel PF Year  1994
Journal  Immunol Today Volume  15
Issue  3 Pages  121-6
PubMed ID  8172644 Mgi Jnum  J:17120
Mgi Id  MGI:65172 Doi  10.1016/0167-5699(94)90155-4
Citation  Zipfel PF, et al. (1994) Complement factor H and related proteins: an expanding family of complement-regulatory proteins?. Immunol Today 15(3):121-6
abstractText  Recently, several factor-H-related molecules have been identified in humans and mice, initiating new interest in this group of serum proteins. Although no complement-regulatory activity has been demonstrated yet for the human factor-H-related proteins, the immunological and structural similarities to factor H suggest overlapping functions. Here, Peter Zipfel and Christine Skerka review these similarities and suggest a new nomenclature to identify members of the factor-H-related family.
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