First Author | Zipfel PF | Year | 1994 |
Journal | Immunol Today | Volume | 15 |
Issue | 3 | Pages | 121-6 |
PubMed ID | 8172644 | Mgi Jnum | J:17120 |
Mgi Id | MGI:65172 | Doi | 10.1016/0167-5699(94)90155-4 |
Citation | Zipfel PF, et al. (1994) Complement factor H and related proteins: an expanding family of complement-regulatory proteins?. Immunol Today 15(3):121-6 |
abstractText | Recently, several factor-H-related molecules have been identified in humans and mice, initiating new interest in this group of serum proteins. Although no complement-regulatory activity has been demonstrated yet for the human factor-H-related proteins, the immunological and structural similarities to factor H suggest overlapping functions. Here, Peter Zipfel and Christine Skerka review these similarities and suggest a new nomenclature to identify members of the factor-H-related family. |