First Author | Meruelo D | Year | 1983 |
Journal | J Immunol | Volume | 130 |
Issue | 2 | Pages | 946-50 |
PubMed ID | 6184409 | Mgi Jnum | J:6921 |
Mgi Id | MGI:55393 | Doi | 10.4049/jimmunol.130.2.946 |
Citation | Meruelo D, et al. (1983) A new lymphocyte cell surface antigen, Ly-22.2, controlled by a locus on chromosome 4 and a second unlinked locus. J Immunol 130(2):946-50 |
abstractText | A serum raised by immunizing (B10.A(4R) X B10.HTT)F1 mice against A.AL lymphocytes detects a new antigenic determinant designated Ly-22.2. Ly-22.2 expression is under the control of two independently segregating genes, one of which maps to chromosome 4 adjacent to a locus affecting XenCSA expression. Ly-22.2 is present in varying amounts in all lymphoid organs, but appears to be expressed primarily on T lymphocytes. Ly-22.2 is not detectable in brain, kidney, lung, liver, or erythrocytes. Strain distribution studies show Ly-22.2 is present in all strains examined except B10-derived congenic strains. It is of interest that C57BL/6 and C57BL/10 mice differ in the expression of this antigen. |