Primary Identifier | MGI:3690216 | Allele Type | Targeted |
Gene | Bcl2 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A mutated cAMP responsive element was introduced into the promoter of Bcl2. RT-PCR detected that mRNA levels were reduced approximately 3.6-fold in B cells from the mutant mice. |