Primary Identifier | MGI:2180140 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 326623 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable death receptor binding activity. Predicted to be involved in positive regulation of cytokine production. Predicted to act upstream of or within positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in plasma membrane. Orthologous to human TNFSF15 (TNF superfamily member 15). PHENOTYPE: Homozygous targeted mutants display decreased clinical severity in experimental autoimmune encephalomyelitis (EAE) and collagen-induced arthritis. [provided by MGI curators] |