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Allele : Runx1<tm1(RUNX1)Gcg> runt related transcription factor 1; targeted mutation 1, Gerard C Grosveld

Primary Identifier  MGI:3621479 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Runx1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A fragment of human RUNX1 cDNA containing 62 bp of exon 4 and the rest of the coding region was inserted in-frame into the mouse exon 4. IRES sequences were included upstream of both the MN1-TEL (type 1) and the GFP cDNAs. A stop sequence flanked by loxP sites was located between the RUNX1 and IRES-MN1-TEL cDNAs.
  • mutations:
  • Insertion
  • synonyms:
  • MN1-TEL<KI>,
  • MN1-TEL<KI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele