Primary Identifier | MGI:3621479 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Runx1 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A fragment of human RUNX1 cDNA containing 62 bp of exon 4 and the rest of the coding region was inserted in-frame into the mouse exon 4. IRES sequences were included upstream of both the MN1-TEL (type 1) and the GFP cDNAs. A stop sequence flanked by loxP sites was located between the RUNX1 and IRES-MN1-TEL cDNAs. |