| First Author | Chien YH | Year | 1984 |
| Journal | Nature | Volume | 309 |
| Issue | 5966 | Pages | 322-6 |
| PubMed ID | 6328306 | Mgi Jnum | J:7463 |
| Mgi Id | MGI:55933 | Doi | 10.1038/309322a0 |
| Citation | Chien YH, et al. (1984) Somatic recombination in a murine T-cell receptor gene. Nature 309(5966):322-6 |
| abstractText | A putative T-cell receptor gene was isolated from the DNA of the helper hybridoma, 2B4 . Analysis of the sequence components of this rearranged gene indicates the presence of separate variable (V), diversity (D) and joining (J) region elements analogous to those of heavy-chain immunoglobulins. These findings further support the belief that the products of this locus are involved in antigen recognition by T cells. There is no evidence of somatic mutation between the putative germ-line and the expressed variable-region gene. |
