| Primary Identifier | MGI:1194503 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 53313 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including calcium-dependent ATPase activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and transmembrane transporter binding activity. Predicted to be involved in calcium ion transport from cytosol to endoplasmic reticulum; endoplasmic reticulum calcium ion homeostasis; and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to act upstream of or within monoatomic ion transport. Located in endoplasmic reticulum. Is expressed in diaphragm. Orthologous to human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3). PHENOTYPE: Homozygous mutation of this gene results in reduced endothelial-dependent relaxation in the aorta. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
