| Primary Identifier | MGI:3838539 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Clgn-Adam3)47Osb |
| Strain of Origin | 129S1/Sv and 129X1/SvJ and CD-1 | Is Recombinase | false |
| Is Wild Type | false |
| description | The transgene construct was microinjected into fertilized oocytes heterozygous for Adam3tm1Ihig on a mixed strain (129S1/Sv, 129X1/SvJ and CD-1) background. |
| molecularNote | This transgene comprises a full length cDNA encoding C-terminal polyhistidine-tagged mouse ADAM3 [a disintegrin and metallopeptidase domain 3 (cyritestin)] followed by a bovine globin polyadenylation signal and expressed under control of the testis specific promoter of the mouse calmegin gene. Western blot analysis demonstrated the presence of ADAM3 in both testis and sperm of homozygous Adam3tm1Ihig mice bearing this transgene. |
