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Allele : Pax6<Leca1> paired box 6; lens corneal adhesion 1

Primary Identifier  MGI:1934622 Allele Type  Chemically induced (ENU)
Gene  Pax6 Inheritance Mode  Not Specified
Strain of Origin  BALB/c Is Recombinase  false
Is Wild Type  false
description 

The phenotype in the Pax6Leca allelic series (Leca 1-4) produced a range of similar but variable eye phenotypes, with slightly smaller eyes and occasional adhensions between the lens and cornea.

molecularNote  The mutation underlying the phenotype in Leca1 mice was identified as a T to A substitution at nucleotide position 971 of the Pax6 gene. The mutation occurs in exon 10 and introduces the Val270Glu change in the homeobox domain of the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Gena238,
  • Gena238,
  • Gena 238,
  • Gena 238
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele