First Author | Duboule D | Year | 1986 |
Journal | EMBO J | Volume | 5 |
Issue | 8 | Pages | 1973-80 |
PubMed ID | 3019676 | Mgi Jnum | J:8427 |
Mgi Id | MGI:56894 | Doi | 10.1002/j.1460-2075.1986.tb04452.x |
Citation | Duboule D, et al. (1986) A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus. EMBO J 5(8):1973-80 |
abstractText | A new murine homeo-box (Hox1-3) has been isolated and studied with respect to its structure and transcriptional pattern. This homeo-box is part of a gene which is specifically regulated during mouse prenatal development and expressed in a restricted number of teratocarcinoma tumours as well as in adult testis. Hox1-3 is shown to be a member of a cluster of at least four homeo-boxes lying within a 75-kb segment of DNA on mouse chromosome 6. The structure of the whole cluster, the Hox-1 locus is presented. |