Primary Identifier | MGI:3779933 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 671232 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Acts upstream of or within several processes, including ectopic germ cell programmed cell death; ncRNA transcription; and spermatocyte division. Predicted to be located in cytoplasm. Is expressed in germ cell of testis; ovary; and testis. Orthologous to human TOPAZ1 (testis and ovary specific TOPAZ 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with abnormal meiosis and apoptosis of male germ cells. [provided by MGI curators] |