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Allele : Ryr1<tm1.1Msnr> ryanodine receptor 1, skeletal muscle; targeted mutation 1.1, Gerhard Meissner
Primary Identifier  MGI:5484746 Allele Type  Targeted
Attribute String  Not Specified Gene  Ryr1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A nucleic acid base change was inserted into exon 74 causing a change in amino acid 3625 from Leucine to Aspartic Acid (L3625D). In addition, a floxed cassette composed of a neomycin gene and a testis-specific angiotensin-convertingenzyme promoter driving expression of cre recombinase was inserted in intron 76. Germline transmission therefore results in excision of the neomycin selection cassette and the cre recombinase.
  • mutations:
  • Single point mutation
  • synonyms:
  • Ryr1<D>,
  • Ryr1<D>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Carried By

Trail: Allele

0 Driven By

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Trail: Allele




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