| Primary Identifier | MGI:1306802 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 16413 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables protein kinase binding activity. Involved in several processes, including integrin activation; positive regulation of stress fiber assembly; and regulation of cell-substrate adhesion. Located in several cellular components, including cytoskeleton; lamellipodium; and ruffle. Is expressed in left lung and right lung. Orthologous to human ITGB1BP1 (integrin subunit beta 1 binding protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit postnatal lethality, reduced weight and length, reduced ossification, and skull and skeleton abnormalities. Mice homozygous for a gene trap mutation are viable and do not exhibit any obvious abnormalites. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
