| First Author | Chen F | Year | 2007 |
| Journal | Cancer Res | Volume | 67 |
| Issue | 23 | Pages | 11093-8 |
| PubMed ID | 18056430 | Mgi Jnum | J:128483 |
| Mgi Id | MGI:3767335 | Doi | 10.1158/0008-5472.CAN-07-1576 |
| Citation | Chen F, et al. (2007) Nuclear factor-kappaB, an unappreciated tumor suppressor. Cancer Res 67(23):11093-8 |
| abstractText | The notion that nuclear factor-kappaB (NF-kappaB) is a tumor-promoting transcription factor has become a widely accepted dogma in biology. However, recent findings suggest an inhibitory role for NF-kappaB in carcinogenesis and tumorigenesis. Although the tumor suppressor-like effect of NF-kappaB remains to be rigorously established by further studies using cellular and animal models, these latest findings warrant caution with respect to blockage of NF-kappaB activation as a broad strategy in treating cancers. |
