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Protein Coding Gene : Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif 20

Primary Identifier  MGI:2660628 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  223838
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables metalloendopeptidase activity. Acts upstream of or within several processes, including extracellular matrix organization; negative regulation of apoptotic process; and positive regulation of melanocyte differentiation. Located in extracellular space. Is expressed in several structures, including incisor; integumental system; neural tube; tongue muscle; and trunk mesenchyme. Orthologous to human ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20).
PHENOTYPE: Mice homozygous for spontaneous or ENU-induced mutations exhibit abnormal coat/hair pigmentation, including a typical white belt phenotype. [provided by MGI curators]
  • synonyms:
  • ADAM metallopeptidase with thrombospondin type 1 motif 20,
  • ADAMTS-20,
  • belted,
  • MGI:88212,
  • bt,
  • MGD-MRK-1678,
  • Adamts20

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For