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Publication : Immune evasion of tumor cells using membrane-bound complement regulatory proteins.

First Author  Gorter A Year  1999
Journal  Immunol Today Volume  20
Issue  12 Pages  576-82
PubMed ID  10562709 Mgi Jnum  J:58717
Mgi Id  MGI:1349518 Doi  10.1016/s0167-5699(99)01537-6
Citation  Gorter A, et al. (1999) Immune evasion of tumor cells using membrane-bound complement regulatory proteins. Immunol Today 20(12):576-82
abstractText  Membrane-bound complement regulatory proteins (mCRPs) play an important role in the protection of cells from complement-mediated injury. It is now apparent that malignant tumor cells also express these proteins to escape complement attack. Here, Arko Gorter and Seppo Meri discuss the implications of complement resistance for the immunotherapeutic treatment of solid tumors with monoclonal antibodies.
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