| Primary Identifier | MGI:1857807 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Aqp1 |
| Transmission | Germline | Strain of Origin | C57BL/6J x (Rb(11.16)2H x Rb(16.17)32Lub)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 1.8 kb neomycin cassette replaced part of the exon 1 coding sequence and ~1.3 kb of intron 1. Northern blot analysis of kidney, lung, eye, spleen, and heart homogenates from homozygous mutant mice did not detect full-length transcripts. Western blots of kidney, lung, eye, spleen, and heart homogenates from homozygous mutant mice did not detect showed no detectable encoded protein. |
