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Protein Coding Gene : Sinhcaf SIN3-HDAC complex associated factor

Primary Identifier  MGI:1929091 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  56306
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in negative regulation of cell differentiation and positive regulation of cell population proliferation. Predicted to be part of Sin3-type complex. Is expressed in several structures, including central nervous system; early embryo; gut; heart; and lung. Orthologous to human SINHCAF (SIN3-HDAC complex associated factor).
PHENOTYPE: Homozygous null mice exhibit hypoplasia of visceral organs and die after E10.5 but before birth. Embryos exhibit growth retardation, cardiac defects, neural tube defects, gut rotation abnormalities, and incomplete lobulation of lungs. [provided by MGI curators]
  • synonyms:
  • pluripotent cell-specific 1,
  • SIN3-HDAC complex associated factor,
  • MGI:1097676,
  • Sinhcaf,
  • Fam60a,
  • Tera,
  • Pptcs1,
  • family with sequence similarity 60, member A,
  • teratocarcinoma expressed, serine rich

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For