Primary Identifier | MGI:5752890 | Allele Type | Targeted |
Gene | Dnmt1 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 13 was replaced with a floxed neomycin resistance cassette and a modified exon 13 in which nucleotide substitutions replaced the amino acids ESH with ASA within the mouse-rat differential region of the intrisically disordered domain (IDD). Cre-mediated recombination removed the selection cassette. |