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Allele : Cask<tm1.1Sud> calcium/calmodulin dependent serine protein kinase; targeted mutation 1.1, Thomas C Sudhof

Primary Identifier  MGI:3699428 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cask
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Crossing Casktm1Sud mutants with cre-expressing mice results in excision of the floxed exon and neomycin cassette creating a null allele. Cask expression is decreased ~33% in heterozygotes and is abolished in homozygotes.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • CASK KO,
  • CASK KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele