Primary Identifier | MGI:3699428 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cask |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Crossing Casktm1Sud mutants with cre-expressing mice results in excision of the floxed exon and neomycin cassette creating a null allele. Cask expression is decreased ~33% in heterozygotes and is abolished in homozygotes. |