Primary Identifier | MGI:5548298 | Allele Type | Targeted |
Attribute String | Hypomorph, Modified isoform(s), Reporter | Gene | Rorb |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A GFP replaced the coding sequence in the beta 1 first coding exon. The final allele lacks the self-excising neomycin resistance cassette inserted downstream of the GFP gene. Western blot analysis confirmed the absence of isoform beta 1 but expression of isoform beta 2. |