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Protein Coding Gene : Vps37a vacuolar protein sorting 37A
Primary Identifier  MGI:1261835 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  52348
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within protein transport. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of ESCRT I complex. Is expressed in several structures, including branchial arch; facial prominence; heart; limb bud; and neural fold. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 53. Orthologous to human VPS37A (VPS37A subunit of ESCRT-I).
  • synonyms:
  • D8Ertd531e,
  • vacuolar protein sorting 37A,
  • MGI:1923157,
  • MGI:1914764,
  • DNA segment, Chr 8, ERATO Doi 531, expressed,
  • Vps37a,
  • 4930592A21Rik,
  • expressed sequence AW261445,
  • 2210018P21Rik,
  • RIKEN cDNA 2210018P21 gene,
  • RIKEN cDNA 4930592A21 gene,
  • AW261445,
  • MGI:2142784
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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