Primary Identifier | MGI:2449013 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Itgb1bp2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exons 1-4 with a lacZ-neo cassette via homologous recombination. Western blot analysis of skeletal and cardiac muscle proteins confirmed the absence of gene expression in homozygous mutant animals. |