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Protein Coding Gene : Etv5 ets variant 5

Primary Identifier  MGI:1096867 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  104156
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including neuromuscular synaptic transmission; regulation of branching involved in mammary gland duct morphogenesis; and skeletal muscle acetylcholine-gated channel clustering. Located in plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Used to study T-cell adult acute lymphocytic leukemia. Orthologous to human ETV5 (ETS variant transcription factor 5).
PHENOTYPE: Homozygous null mice display either male infertility, small testes, azoospermia, and failure to maintain spermatogonia or they are prenatally lethal. Preaxial polydactyly has also been observed. [provided by MGI curators]
  • synonyms:
  • erm,
  • RIKEN cDNA 8430401F14 gene,
  • ets variant 5,
  • 8430401F14Rik,
  • 1110005E01Rik,
  • MGI:1923002,
  • RIKEN cDNA 1110005E01 gene,
  • Etv5,
  • MGI:1915818

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For