| Primary Identifier | IPR042917 | Type | Family |
| Short Name | MIXL1 |
| description | Mixl1 is a homeobox transcription factor essential for the patterning of axial mesendodermal structures during early embryogenesis [, ]. It interacts with the T-box protein Brachyury and related members of the T-box family of transcription factors; this interaction negatively regulates Mixl1 transcriptional activity []. In mice, enforced expression of Mixl1 results in transplantable AML (acute myeloid leukemia), suggesting a leukemogenic potential for Mixl []. |
