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Allele : Athsq1<C57BL/6J> atherosclerosis susceptibility QTL 1; C57BL/6J
Primary Identifier  MGI:2155676 Allele Type  QTL
Gene  Athsq1 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
description 

Trait Annotation
(using the Vertebrate Trait Ontology)

organ system trait
circulatory system morphology trait
blood vessel morphology trait
aorta integrity trait - VT:0010602
aortic root lesion size is less relative to MOLF/Ei in female mice only - J:70259
Wang et al (J:140288) identified Athsq1 in F2 animals homozygous for Apoetm1Unc but now considered Athsq3.
molecularNote  This allele confers resistance to atherosclerosis in female animals compared to MOLF/Ei. This allele confers increased aortic lesion area in females on a high fat diet compared to C3H/HeJ.
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele




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